Jim Mansfield
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Jim's List of Publications

Last updated: January 12, 2013

Publications

46) Lei Zhu, Ning Guo, Quanzheng Li, Ying Ma, Orit Jacboson, Seulki Lee, Hak Soo Choi, James R. Mansfield, Gang Niu, Xiaoyuan Chen “Dynamic PET and Optical Imaging and Compartment Modeling using a Dual-labeled Cyclic RGD Peptide Probe” Theranostics 2012; 2(8):746-756.

45)  Elizabeth M. C. Hillman, Cyrus B. Amoozegar, Tracy Wang, Addason F. H. Mccaslin, Matthew B. Bouchard, James Mansfield, Richard M. Levenson “In vivo optical imaging and dynamic methods for biomedical research” Phil. Trans. R. Soc. A, in press.

44)  Mansfield, J.R. “Cellular context in epigenetics: Quantitative multicolor imaging and automated per-cell analysis of miRNAs and their putative targets” Methods 52 (2010) 271–280.

43)  Mansfield, J. “Distinguished Photons: A Review of In Vivo Spectral Fluorescence Imaging in Small Animals” Current Pharmaceutical Biotechnology 2010, 11,628-638.

42)  James R. Mansfield and Richard M. Levenson “Paving a New Path: Multispectral Imaging in Pathology” inFocus Magazine, June 2009.

41)  James R. Mansfield, Clifford Hoyt, and Richard M. Levenson “Visualization of Microscopy-Based Spectral Imaging Data from Multi-Label Tissue Sections” Current Protocols in Molecular Biology 14.19.1-14.19.15, October 2008.

40) Bouchard MB, MacLaurin SA, Dwyer PJ, Mansfield J, Levenson R, Krucker T. “Technical considerations in longitudinal multispectral small animal molecular imaging.” J Biomed Opt. 2007 Sep-Oct;12(5):051601.

39)  Levenson, Richard M.; Mansfield, James R. “Multispectral imaging in medicine and biology: Slices of life”, Cytometry A. 2006 Aug 1;69(8):748-58.

38)  Leopoldo C. Cancio, MD; Andriy I Batchinsky, MD; James R Mansfield, MSc; Svetlana Panasyuk, PhD; Katherine Hetz, BS; David Martini, MS; Bryan S Jordan, RN, MSN; Brian Tracey, PhD; Jenny E Freeman, MD “Hyperspectral Imaging: A New Approach to the Diagnosis of Hemorrhagic Shock”, J. Trauma, 2006 May;60(5):1087-95.

37)  James R. Mansfield, Clifford C. Hoyt, Peter J. Miller, Richard M. Levenson “Distinguished photons: increased contrast with multispectral in-vivo fluorescence imaging”, Biotechniques, Vol. 39 Supplement: pp S25-S29 (Dec 2005).

36)  Mansfield, James R.; Gossage, Kirk W; Hoyt, Clifford; Levenson, Richard “Autofluorescence removal, multiplexing and automated analysis methods for in-vivo fluorescence imaging” Journal of Biomedical Optics, 2005 Jul-Aug; 10(4): 41207.

35)  Gillies, Robert; Levin, Robin K.; Mansfield, James R.; Hopmeier, Michael J.; Freeman, Jenny E. “Use of hyperspectral imaging to profile cutaneous responses to bioweapons: a concept paper” Proc SPIE, Vol 5072, pp. 32-44 (2003).

24)  Kellicut Dwight C.; Weiswasser Jonathan M.; Arora Subodh; Freeman Jenny E.; Lew Robert A.; Shuman Charles; Mansfield James R.; Sidawy Anton N. “Emerging technology: Hyperspectral imaging” Perspectives in vascular surgery and endovascular therapy, 2004, vol. 16, no. 1, pp. 53-57.

33)  J.M.G. Canvin, S. Bernatsky, C.A. Hitchon, M. Jackson, M.G. Sowa, J.R. Mansfield, H.H. Eysel, H.H. Mantsch, H.S. El-Gabalawy, “Infrared spectroscopy: shedding light on synovitis in patients with rheumatoid arthritis” Rheumatology (Oxford), 2003 Jan 42:76-82.

32)  Michael Attas, Edward Cloutis, Douglas Goltz, Claudine Majzels, James R. Mansfield, Henry H. Mantsch “Spectroscopic Imaging in Art Conservation: A New Tool for Materials Investigation” Leonardo: Journal of the International Society for the Arts, Sciences and Technology Volume 36, Number 4, 2003, 304-307.

31)  Robert Gillies, Jenny E. Freeman, Leopoldo C. Cancio, Derek Brand, Michael Hopmeier, James R. Mansfield “Systemic Effects of Shock and Resuscitation Monitored by Visible Hyperspectral Imaging” Diabetes Technology & Therapeutics, Volume 5, Number 5, 2003, 847-855.

30)  Attas, M.; Cloutis, E.; Collins, C.; Goltz, D.; Majzels, C.; Mansfield, J.R.; Mantsch, H.H., “Near-infrared spectroscopic imaging in art conservation: investigation of drawing constituents” Journal of Cultural Heritage, Volume 4, Issue 2, April 2003, Pages 127-136.

29)  S.P. Nighswander-Rempel, R.A. Shaw, J.R. Mansfield, M. Hewko, V.V. Kupriyanov, H.H. Mantsch, "Regional Variations in Myocardial Tissue Oxygenation Mapped by Near-Infrared Spectroscopic Imaging," Journal of Molecular and Cellular Cardiology, 34, 1195-1203 (2002).

28)  Leopoldo C. Cancio, Derek Brand, Jeffrey Kerby, Jenny E. Freeman, Michael Hopmeier, James R. Mansfield “Visible Hyperspectral Imaging: Monitoring The Systemic Effects of Shock and Resuscitation” Proc. SPIE, Vol. 4614, 159-168.

27)  L.M. McIntosh, M. Jackson, H.H. Mantsch, J.R. Mansfield, A.N. Crowson, and J.W.P. Toole. "Near-Infrared Spectroscopy For Dermatological Applications," Vibrational Spectroscopy, 28, 53-58, 2002.

26)  J.R. Mansfield, M. Attas, C. Majzels, E. Cloutis, C. Collins, and H.H. Mantsch, "Near Infrared Spectroscopic Reflectance Imaging: A New Tool in Art Conservation," Vibrational Spectroscopy, 28, 59-66, 2002.

25)  L.M. McIntosh, J.R. Mansfield, A.N. Crowson, M. Jackson, H.H. Mantsch, “Infrared Imaging of Skin Lesions” Proc. SPIE, Vol. 4577, 226-229, 2002.

24)  Laura M. McIntosh, Randy Summers, Michael Jackson, Henry H. Mantsch, James R. Mansfield, Marilyn Howlett, A. Neil Crowson, and John W. P. Toole “Towards Non-Invasive Screening of Skin Lesions by Near-Infrared Spectroscopy” Journal of Investigative Dermatology 116:175-181, 2001.

23)  R.A. Shaw, J.R. Mansfield, S.P. Rempel, S. Low-Ying, V.V. Kupriyanov, & H.H. Mantsch. “Analysis of Biomedical Spectra and Images: From Data to Diagnosis.” Journal of Molecular Structure (Theochem), 500, 129-138 2000.

22)  R. Salzer, G. Steiner, H.H. Mantsch, J. Mansfield, & N.E. Lewis. “Infrared and Raman Imaging of Biological and Biomimetic Samples.” Fresenius Journal of Analytical Chemistry, 366, 712-726 2000.

21)  R.A. Shaw, J.R. Mansfield, V.V. Kupriyanov, & H.H. Mantsch. “In vivo Optical/Near-Infrared Spectroscopy and Imaging of Metalloproteins.” Journal of Inorganic Biochemistry, 79, 285-293 2000.

20)  J.R. Mansfield, M.G. Sowa, & H.H. Mantsch. Development of LCTF-based Visible and Near-IR Spectroscopic Imaging Systems for Macroscopic Samples. Proc SPIE, 3920, 99-107 2000.

19)  L.M. McIntosh, J.R. Mansfield, A.N. Crowson, J.W.P. Toole, H.H. Mantsch, & M. Jackson. Classification of Infrared Spectra from Skin Tumours. Proc SPIE, 3907, 126-135 2000.

18)  Mansfield, J.R.; McIntosh, L.M.; Jackson, M.; Crowson, A.N.; Mantsch, H.H. "Search Engines for Infrared Microscopic Maps: Linear Discriminant Analysis using an External Training Set" Applied Spectroscopy, 53, 1323-1330 1999. 

17)  McIntosh, L.M.; Mansfield, J.R.; Crowson, N.; Mantsch, H.H.; Jackson, M. “Analysis and Interpretation of Infrared Microscopic Maps: Visualization and Classification of Skin Components” Biospectroscopy, 265-275 1999.

16)  Jackson, M.; Mansfield, J.R.; Dolenko, B.; Somorjai, R.L.; Mantsch, H.H.; Watson, P.H. “Classification of breast tumors by grade and steroid receptor status using pattern recognition analysis of infrared spectra.” Cancer Prevention and Detection, 23, 245-253, 1999.

15)  Mansfield, J.R.; Mazjels, C; Collins, C.; Cloutis, E.; Mantsch, H.H. “Near Infrared Spectroscopic Reflectance Imaging: Supervised versus Unsupervised Analysis Using an Art Conservation Application” Vibrational Spectroscopy, 19, 33-45, 1999.

14)  Mansfield, J.R.; Sowa, M.G.; Mantsch, H.H. “Near Infrared Spectroscopic Reflectance Imaging: Methods for Functional Imaging and In-Vivo Monitoring” Proc SPIE. 3597, 222-233 1999.

13)  Mansfield, J.R.; Sowa, M.G.; Payette, J.; Badur; Stranc, F.; Mantsch, H.H. “A Fuzzy C-Means Clustering Approach to the Analysis of Multispectral Images of the Rat Dorsal Skin Flap” IEEE Transactions in Medical Imaging, 6: 1011-1018, 1998.

12)  M.G. Sowa, J.R. Payette, M.D. Hewko, J.R. Mansfield, H.H. Mantsch “Hemodynamic information obtained by statistical analysis of near-IR spectroscopic images” Proc SPIE. (Infrared Spectroscopy: New Tool in Medicine) 3257: 296-306, 1998.

11)  M. Jackson, K. Kim, J. Tetteh, J.R. Mansfield, B. Dolenko, R.L. Somorjai, F.W. Orr, P.H. Watson, H.H. Mantsch “Cancer diagnosis by infrared spectroscopy: methodological aspects” Proc SPIE (Infrared Spectroscopy: New Tool in Medicine) 3257: 24-34, 1998.

10)  Mansfield, J.R.; Sowa, M.G.; Scarth, G.B.; Mantsch, H.H. “The Use of Fuzzy C-Means Clustering in the Analysis of Spectroscopic Imaging Data” Analytical Chemistry, 1997, 69, 3370-3374.

9)   Mansfield, J.R.; Sowa, M.G.; Scarth, G.B.; Somorjai, R.L.; Mantsch, H.H. “Fuzzy C-Means Clustering and Principal Component Analysis of Time Series from Near-Infrared Imaging of Forearm Ischemia” Computerized Medical Imaging and Graphics, 21:5, 1997, 299-308.

8)   M.G. Sowa, J.R. Mansfield, M. Jackson, J.C. Docherty, R. Deslauriers, and H.H. Mantsch, "FT-IR/NIR Assessment of Ischemic Damage in the Rat Heart" Mikrochimica Acta [suppl.], 1997, 14, 451-453. 

7)   M.G. Sowa, J.R. Mansfield, G.B. Scarth, H.H. Mantsch "Noninvasive Assessment of Regional and Temporal Variations in Tissue Oxygenation by Near Infrared Spectroscopy and Imaging" Applied Spectroscopy 1997, 51:2, 143-152. 

6)   Mantsch, H.H., Eysel, H., Jackson, M., Liu, K.-Z., Mansfield, J.R., Schultz, C., Shaw, R.A. and Sowa, M. “Emerging medical applications of infrared technologies.” In Spectroscopy of Biological Molecules: Modern Trends” (Carmona, P., Navarro, R. and Hernanz, R.A., Eds.): Kluwer Academic Publ., 1997, 421-424

5)   Loeb, Stephen J; Mansfield, James R “Platinum(II) complexes of the tridentate thioether ligands RS(CH2)3S(CH2)3SR (R = Et, i-Pr, Ph). Structures of [PtCl(i-PrS(CH2)3S(CH2)3 Si-Pr)][BF4], [PtI(PhS(CH2)3S(CH2)3SPh)][BF4], and [Pt(PPh3)(i-PrS(CH2)3S(CH2)3Si-Pr)][BF4]2•CH2Cl2Canadian Journal of Chemistry, 1996, 74:7, 1377-91.

4)   L.-P. Choo, J.R. Mansfield, N. Pizzi, R.L. Somorjai, M. Jackson, W.C. Halliday, and H.H. Mantsch, “Infrared Spectra of Human Central Nervous System Tissue: Diagnosis of Alzheimer's Disease by Multivariate Analysis” Biospectroscopy 1995, 1, 141-148. 

3)   N. Pizzi, L.-P. Choo, J.R. Mansfield, M. Jackson, W.C. Halliday, H.H. Mantsch, and R.L. Somorjai “Neural Network Classification of Infrared Spectra of Control and Alzheimer's Disease Tissue” Artificial Intelligence in Medicine 1995, 7, 67-79. 

2)   L.-P. Choo, J.R. Mansfield, N. Pizzi, R.L. Somorjai, M. Jackson, W.C. Halliday, and H.H. Mantsch “Classification of Infrared Spectra of Alzheimer's Disease by Multivariate Analysis” Spectroscopy of Biological Materials, J.C. Merlin et al. (eds.), Kluwer Academic Publishers 1995, 587-488. 

1)   Schaefer, T., Mansfield, J.R., Hruska, F.E., Sebastian, R., “The solvent dependence of the small internal barrier to rotation in 3,5-dichlorobenzyl fluoride.” Canadian Journal of Chemistry 1992, 70, 1750-1753. 

 

Issued Patents

  1. US #7,289,835 Multivariate analysis of green to ultraviolet spectra of cell and tissue samples
  2. US #7,013,172 Hyperspectral imaging calibration device
  3. US #6,810,279 Hyperspectral imaging calibration device
  4. US #6,424,859 Diagnosis of rheumatoid arthritis in vivo using a novel spectroscopic approach
  5. US #6,640,130 Integrated imaging apparatus
  6. US #6,721,582 Non-invasive tissue glucose level monitoring 
  7. US #7,899,518 Non-invasive tissue glucose level monitoring

 

Published Patent Applications

  1. US 20040236229 Integrated imaging device
  2. EP 1226462 Interface medium for tissue surface probe 
  3. WO 03010510 Adjunct quantitative system and method for non-invasive measurement of in vivo analytes
  4. WO 03010561 Optical coupler for measuring tissue fluorescence
  5. US 20010034477 Multivariate analysis of green to ultraviolet spectra of cell and tissue samples 
  6. US 20020058864 Reduction of spectral site to site variation
  7. US 20020133080 Layered calibration standard for tissue sampling
  8. US 20020010401 Pre- and post-processing of spectral data for calibration using multivariate analysis techniques 
  9. US 20010039483 Reduction of inter-subject variation via transfer standardization

Short Courses

  1. Richard M. Levenson, James R. Mansfield, “Spectral imaging in medicine and biology” SPIE, San Jose, 2006
  2. Richard M. Levenson, James R. Mansfield, “Spectral imaging in medicine and biology” SPIE, San Jose, 2005

 

Conference Presentations

  1. James R. Mansfield “Distinguished photons: increasing sensitivity and multiplexing for in-vivo fluorescence imaging with Maestro” Stanford Small Animal Imaging Workshop, Palo Alto, November, 2005.
  2. Richard M. Levenson, James R. Mansfield “Multispectral Imaging: From Microscopy to Mice” Eastern Analytical Symposium, Somerset, NJ, 2005.
  3. James R. Mansfield, Richard Levenson “In-Vivo Fluorescence Imaging of Small Animals by Multispectral Imaging” Optics East, Boston, MA, 2005.
  4. James R. Mansfield “Increasing contrast and multiplexing for small animal fluorescence imaging using spectral imaging” Federation of Applied Chemistry and Spectroscopy Societies, Quebec City, Canada, 2005.
  5. James R. Mansfield, Kirk W. Gossage and Richard M. Levenson “Beyond autofluorescence removal: automated analysis methods for multispectral in-vivo imaging”, European Congress on Biological Optics, Munich, Germany, 2005
  6. Organized the Biophotonics Instrumentation symposium for PhAST, Baltimore, May, 2005.
  7. Richard M. Levenson, James R. Mansfield  Increased contrast and sensitivity for in-vivo fluorescence imaging”, Society for Molecular Imaging Meeting, Cologne, Germany, 2005.
  8. Richard M. Levenson, James R. Mansfield, Roger Y. Tsien, Emilia S. Olson, Lei Wang, “Multiplexing fluorescent agents with multispectral imaging: microscopy and in-vivo examples” American Academy of Cancer Researchers Meeting, San Diego, CA, 2005.
  9. James R. Mansfield, Richard Levenson, Robert Hoffman “Increasing Contrast in In-Vivo Fluorescence Imaging of Small Animals by Multispectral Imaging”, American Academy of Cancer Researchers Meeting, San Diego, CA, 2005
  10. Richard Levenson, James R. Mansfield,  “Small-animal fluorescence detection using the Maestro™ multispectral imaging system” Society for Molecular Imaging, St. Louis, MO, 2004
  11. James R. Mansfield, Richard Levenson “Chromophore/fluorophore multiplexing and tissue autofluorescence removal using multispectral imaging” Society for Molecular Imaging, St. Louis, MO, 2004
  12. James R. Mansfield “Fluorescent Dye Multiplexing and tissue Autofluorescence Removal Using Multispectral Imaging” Microscopy and Microbeam Analysis, Savannah, GA, 2004.
  13. James R. Mansfield, Robert A. Lew, E. Neil Lewis, Jenny Freeman, Dwight Kellicut, Anton Sidawy Hyperspectral Imaging of Diabetic Foot Conditions, Eastern Analytical Society Meeting, Somerset, NJ, 2003
  14. Leopold C. Cancio, Derek Brand, Jeffery Kerby, Jenny Freeman, Michael Hopmeier, and James R. Mansfield “Visible hyperspectral imaging: monitoring the systemic effects of shock and resuscitation  Proc. SPIE, Vol 4614, March 2002, pp. 159-168.   
  15. L. Cancio, A. Batchinsky, E.N. Lewis, J. Freeman, R.A. Lew, J.R. Mansfield* Non-Invasive Determination of Hypovolemic Shock Using Hyperspectral Imaging, Federation of Applied Chemistry and Spectroscopy Societies (FACSS) Annual Meeting, Ft. Lauderdale, FL, 2003.
  16. Andrew Bushmakin, Robert A. Lew, Pierre Trepagnier, James R. Mansfield* “Reshuffling: The Use of Permutation Tests in the Validation of Cross-Validation”, Shedding New Light on Disease, Reims, France, June 2002.
  17. L.M. McIntosh, J.R. Mansfield,* A.N. Crowson, M. Jackson, H.H. Mantsch, “Infrared Imaging of Skin Lesions” Proc. International Society of Optical Engineers (SPIE), Vol. 4577, 226-229, 2002.
  18. J.R. Mansfield, M.E. Leventon, M. Hopmeier, J.E. Freeman, L. Marcucci, M. Schaberle, K. Zuzak, E.N. Lewis "Biomedical Applications of a Dual Hyperspectral Thermal IR Imaging System", Federation of Applied Chemistry and Spectroscopy Societies (FACSS) Annual Meeting, Nashville, TN, Oct., 2000, Paper 260.
  19. J.R. Mansfield, M.G. Sowa, & H.H. Mantsch. Development of LCTF-based Visible and Near-IR Spectroscopic Imaging Systems for Macroscopic Samples. Proc. International Society of Optical Engineers (SPIE), 3920, 99-107 2000.
  20. James R. Mansfield, Michael G. Sowa, R. Anthony Shaw, Valerian Kupriyanov, Henry H. Mantsch Functional Near Infrared Imaging. Federation of Applied Chemistry and Spectroscopy Societies (FACSS) Annual Meeting, Vancouver, BC, 1999.
  21. J.R. Mansfield and H.H. Mantsch* “The Marriage between IR Spectroscopy and Medicine” International Conference on Fourier Transform Spectroscopy (ICOFTS), August 1999.
  22. J.R. Mansfield, M.G. Sowa, J.R. Payette, M.G. Hewko, L. Leonardi, B. Abdulrauf, M.F. Stranc, and H.H. Mantsch. "The Development of Non-Invasive Diagnostics Methods Using Near Infrared Imaging" Canadian Federation of Biological Societies, Winnipeg, Manitoba, June 1999.
  23. J.R. Mansfield, M.G. Sowa, H.H. Mantsch “Near Infrared Spectroscopic Reflectance Imaging: Methods for Functional Imaging and In-Vivo Monitoring” Proc. International Society of Optical Engineers (SPIE), San Jose, CA., January 1999.
  24. J.R. Mansfield, M.G. Sowa, J.R. Payette, H.H. Mantsch “Near Infrared Imaging and Spectroscopy: Methods for Tissue Viability Assessment” Advanced Technological Applications for Combat Casualty Care 1998, Fort Walton Beach, Florida.
  25. J.R. Mansfield, M.G. Sowa, C. Majzels, C. Collins, E. Cloutis H.H. Mantsch* “Near Infrared Spectroscopic Reflectance Imaging: Supervised versus Unsupervised Analysis Using an Art Conservation Application” International Conference on Fourier Transform Spectroscopy (ICOFTS) 1998, Vienna, Austria.
  26. J.R. Mansfield, M.G. Sowa, and H.H. Mantsch "Near Infrared Imaging: A New Tool for Medicine?" The Pittsburgh Conference, Atlanta, GA, 1997.

* Presenting author (if not presented by the first author)


Created by Jim Mansfield. Last Update: January 12, 2013.
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